Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5) Peptide
PIK3R5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981763
Quick Overview for Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5) Peptide (ABIN981763)
Target
PIK3R5
(Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PIK3R5 antibody (Catalog #: ARP55011_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
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Background
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Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit.Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3253 AF128881.1 1-3253
Alias Symbols: F730038I15Rik, FOAP-2, P101-PI3K, p101
Protein Interaction Partner: PIK3CG,PIK3CG
Protein Size: 880 -
Molecular Weight
- 97 kDa
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Gene ID
- 23533
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NCBI Accession
- NM_014308, NP_055123
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UniProt
- Q8WYR1
Target
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