Pyruvate Kinase M2 (PKM2) (Middle Region) Peptide
PKM2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981816
Quick Overview for Pyruvate Kinase M2 (PKM2) (Middle Region) Peptide (ABIN981816)
Target
PKM2
(Pyruvate Kinase M2 (PKM2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV LTKSGRSAHQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PKM2 Antibody(ARP57789_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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Background
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This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Alias Symbols: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1, PKM2
Protein Interaction Partner: RAF1,RAF1,ARAF,EXOSC5,HERC1,NDRG1,OLFM2,PKM2,RAF1,SHBG,SORBS2,ARAF,BANF1,EXOSC5,TRIM63
Protein Size: 531 -
Molecular Weight
- 58 kDa
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Gene ID
- 5315
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NCBI Accession
- NM_002654, NP_002645
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UniProt
- P11980
Target
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