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Polynucleotide Kinase 3'-Phosphatase (PNKP) (Middle Region) Peptide

PNKP Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN981901

Quick Overview for Polynucleotide Kinase 3'-Phosphatase (PNKP) (Middle Region) Peptide (ABIN981901)

Target

PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

Middle Region

Sequence

ALLSASPEVV VAVGFPGAGK STFLKKHLVS AGYVHVNRDT LGSWQRCVTT

Characteristics

This is a synthetic peptide designed for use in combination with anti-PNKP Antibody(ARP52312_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Polynucleotide Kinase 3'-Phosphatase (PNKP) peptide
PNKP Reactivity: Human Host: Synthetic BP, Imm

Polynucleotide Kinase 3'-Phosphatase (PNKP) peptide
PNKP Host: Synthetic BP, WB, IHC

Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) peptide
PNKP Reactivity: Human Host: Synthetic BP, WB

Polynucleotide Kinase 3'-Phosphatase (PNKP) (C-Term) peptide
PNKP Reactivity: Human Host: Synthetic BP, BI

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Background

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Alias Symbols: PNK, MCSZ, EIEE10

Protein Interaction Partner: XRCC1,KRTAP4-12,MAGEA11,MYOZ1,SMAD5,TRIM37,XRCC1,XRCC4,ATAD3B,DDX20,HEATR2,KRTAP4-12,LAS1L,LIG3,LIG4,MAGEA11,MCM3,MYOZ1,NOL3,NOM1,NUP93,POLB,SLC25A12,TRIM37,XRCC1,XRCC4,YWHAQ

Protein Size: 521

Molecular Weight

57 kDa

Gene ID

11284

NCBI Accession

NM_007254, NP_009185

UniProt

Q96T60

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