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POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptide

POU3F3 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN982009

Quick Overview for POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptide (ABIN982009)

Target

POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Characteristics

This is a synthetic peptide designed for use in combination with anti-POU3F3 antibody (Catalog #: ARP33062_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
POU Class 3 Homeobox 3 (POU3F3) peptide
POU3F3 Host: Synthetic BP, Imm

POU Class 3 Homeobox 3 (POU3F3) (C-Term) peptide
POU3F3 Reactivity: Human, Rat Host: Synthetic BP, WB

POU Class 3 Homeobox 3 (POU3F3) (Internal Region) peptide
POU3F3 Reactivity: Human, Rat, Mouse Host: Synthetic BP, BI

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Background

POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].

Alias Symbols: BRN1, OTF8

Protein Interaction Partner: POU3F4,PPP1R15A,SOX10,SOX11,SOX8,POU3F4

Protein Size: 500

Molecular Weight

50 kDa

Gene ID

5455

NCBI Accession

NM_006236, NP_006227

UniProt

P20264

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