POU Domain, Class 4, Transcription Factor 3 (POU4F3) Peptide
POU4F3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN982016
Quick Overview for POU Domain, Class 4, Transcription Factor 3 (POU4F3) Peptide (ABIN982016)
Target
POU4F3
(POU Domain, Class 4, Transcription Factor 3 (POU4F3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-POU4F3 antibody (Catalog #: ARP33065_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
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Background
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POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
Alias Symbols: BRN3C, DFNA15
Protein Size: 338 -
Molecular Weight
- 37 kDa
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Gene ID
- 5459
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NCBI Accession
- NM_002700, NP_002691
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UniProt
- Q15319
Target
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