Periphilin 1 (PPHLN1) (N-Term) Peptide
PPHLN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982059
$160.46
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100 μg
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Quick Overview for Periphilin 1 (PPHLN1) (N-Term) Peptide (ABIN982059)
Target
PPHLN1
(Periphilin 1 (PPHLN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MAYRRDEMWS EGRYEYERIP RERAPPRSHP SDGYNRLVNI VPKKPPLLDR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPHLN1 Antibody(ARP57819_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PPHLN1 (Periphilin 1 (PPHLN1))
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Background
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The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: HSPC206, HSPC232, MGC48786
Protein Interaction Partner: CASP5,PPHLN1,PPL,TGM2,TOMM20,VIM,CASP5,PPL,TOMM20
Protein Size: 374 -
Molecular Weight
- 43 kDa
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Gene ID
- 51535
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NCBI Accession
- NM_201515, NP_958923
Target
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