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PR Domain Containing 1, with ZNF Domain (PRDM1) Peptide

PRDM1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982163
  • Target See all PRDM1 products
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PRDM1 antibody (Catalog #: ARP38013_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Background
    PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

    Alias Symbols: BLIMP1, PRDI-BF1

    Protein Interaction Partner: AES,ATXN1,IRF4,TLE1,TLE2,EHMT2,HDAC1,HDAC2,HIST2H3A,KDM1A,PRMT5,PRMT7,SUV39H1,TLE1,TLE2

    Protein Size: 789
    Molecular Weight
    88 kDa
    Gene ID
    639
    NCBI Accession
    NM_001198, NP_001189
    UniProt
    O75626
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