Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Peptide
PRKAA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982202
Quick Overview for Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Peptide (ABIN982202)
Target
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PRKAA1 antibody (Catalog #: ARP53846_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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Background
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PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: AMPK, AMPKa1, MGC33776, MGC57364
Protein Interaction Partner: ACACA,CAB39,CFTR,EEF2K,GRIK2,MTOR,PFKFB2,PRKAB1,PRKAB2,PRKAG1,PRKAG3,RAF1,TOMM34,CFTR,FNIP1,MTOR,PRKAG1,TSC2
Protein Size: 565 -
Molecular Weight
- 62 kDa
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Gene ID
- 5562
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NCBI Accession
- NM_206907, NP_996790
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UniProt
- Q13131
Target
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