Proteinase 3 (PRTN3) (N-Term) Peptide
PRTN3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982314
Quick Overview for Proteinase 3 (PRTN3) (N-Term) Peptide (ABIN982314)
Target
PRTN3
(Proteinase 3 (PRTN3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- IPQRLVNVVL GAHNVRTQEP TQQHFSVAQV FLNNYDAENK LNDVLLIQLS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PRTN3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRTN3 (Proteinase 3 (PRTN3))
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Background
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PRTN3 is a polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Alias Symbols: ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP4, P29, PR-3, PR3
Protein Interaction Partner: CAMP,ELN,F2R,F2RL1,IL1B,IL32,ITGB2,RELA,SERPINA1,SERPINB1,SERPINB13,SMAD3,TNF,ELN,ITGAM,SERPINA1,SERPINB1
Protein Size: 256 -
Molecular Weight
- 28 kDa
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Gene ID
- 5657
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NCBI Accession
- NM_002777, NP_002768
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UniProt
- P24158
Target
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