Patched 1 (PTCH1) Peptide
PTCH1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN982409
Quick Overview for Patched 1 (PTCH1) Peptide (ABIN982409)
Target
Patched 1 (PTCH1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PTCH1 antibody (Catalog #: ARP44249_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Patched 1 (PTCH1)
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Background
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PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Alias Symbols: PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
Protein Interaction Partner: CCNB1,CCNB1,CDK1,DHH,HIPK2,IHH,SHH,SMO,SMO
Protein Size: 345 -
Molecular Weight
- 37 kDa
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Gene ID
- 5727
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NCBI Accession
- NM_000264
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UniProt
- Q6TKP8
Target
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