Nectin cell adhesion molecule 3 (NECTIN3) (Middle Region) Peptide
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- Target See all nectin-3 (NECTIN3) products
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PDSVKKENKN PVNNLIRKDY LEEPEKTQWN NVENLNRFER PMDYYEDLKM
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PVRL3 Antibody(ARP42447_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Synonyms
- PVRL3 Peptide, CD113 Peptide, CDW113 Peptide, NECTIN-3 Peptide, PPR3 Peptide, PRR3 Peptide, PVRR3 Peptide, 2610301B19Rik Peptide, 3000002N23Rik Peptide, 4921513D19Rik Peptide, AA407785 Peptide, AU016832 Peptide, AW538082 Peptide, nectin cell adhesion molecule 3 Peptide, poliovirus receptor-related 3 Peptide, Nectin3 Peptide, NECTIN3 Peptide, PVRL3 Peptide, nectin3 Peptide
- Background
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Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.
Alias Symbols: CDw113, DKFZP566B0846, FLJ90624, PPR3, PRR3, PVRR3, nectin-3, CD113, CDW113, NECTIN-3
Protein Interaction Partner: MLLT4,PARD3,PVR,PVRL1,PVRL2,MLLT4,PARD3,PVR,PVRL3
Protein Size: 549 - Molecular Weight
- 61 kDa
- Gene ID
- 25945
- NCBI Accession
- NM_015480, NP_056295
- UniProt
- Q9NQS3
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