Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982511
Quick Overview for Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN982511)
Target
PYHIN1
(Pyrin and HIN Domain Family, Member 1 (PYHIN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
-
Background
-
PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 452 -
Molecular Weight
- 51 kDa
-
Gene ID
- 149628
-
NCBI Accession
- NM_198930, NP_945148
Target
-
You are here:
