Queuine tRNA-Ribosyltransferase 1 (QTRT1) Peptide
QTRT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982520
Quick Overview for Queuine tRNA-Ribosyltransferase 1 (QTRT1) Peptide (ABIN982520)
Target
QTRT1
(Queuine tRNA-Ribosyltransferase 1 (QTRT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-QTRT1 antibody (Catalog #: ARP48945_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
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Background
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TRNA-guanine transglycosylase (TGT, EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14, MIM 607274) and a 43-kD catalytic subunit (QTRT1).tRNA-guanine transglycosylase (TGT, EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14, MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]).[supplied by OMIM].
Alias Symbols: FP3235, TGT, TGUT
Protein Interaction Partner: COPS6,NDUFA4L2,SETDB1,SH3GL3,UNC119,ZBTB16,COPS6,NDUFA4L2,SETDB1,SH3GL3,UNC119,ZBTB16
Protein Size: 403 -
Molecular Weight
- 44 kDa
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Gene ID
- 81890
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NCBI Accession
- NM_031209, NP_112486
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UniProt
- Q9BXR0
Target
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