RAB8B, Member RAS Oncogene Family (RAB8B) (C-Term) Peptide
-
- Target See all RAB8B products
- RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FETLTCSSGT LRTLRLKIDD FNDELNKLLE EIEEKNPQLI IDTEKHHPWA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAB8B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))
- Background
-
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).
Alias Symbols: FLJ38125
Protein Interaction Partner: CARD8,PYDC2,MRE11A
Protein Size: 1062 - Molecular Weight
- 120 kDa
- Gene ID
- 51762
- NCBI Accession
- NM_016530, NP_057614
- UniProt
- Q92930
-