RAB8B, Member RAS Oncogene Family (RAB8B) (C-Term) Peptide
Quick Overview for RAB8B, Member RAS Oncogene Family (RAB8B) (C-Term) Peptide (ABIN982581)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- FETLTCSSGT LRTLRLKIDD FNDELNKLLE EIEEKNPQLI IDTEKHHPWA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAB8B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAB8B (RAB8B, Member RAS Oncogene Family (RAB8B))
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Background
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NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).
Alias Symbols: FLJ38125
Protein Interaction Partner: CARD8,PYDC2,MRE11A
Protein Size: 1062 -
Molecular Weight
- 120 kDa
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Gene ID
- 51762
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NCBI Accession
- NM_016530, NP_057614
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UniProt
- Q92930
Target
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