RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (N-Term) Peptide
RABGEF1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982589
Quick Overview for RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (N-Term) Peptide (ABIN982589)
Target
RABGEF1
(RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RABGEF1 antibody (Catalog #: ARP55073_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
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Background
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RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: AP1G1,C19orf50,GGA1,GGA2,RAB33B,RAB4A,RABEP1,RNF11,RNF168,RPS27A,UBB,YWHAB,C19orf50,GGA1,YWHAB,YWHAG
Protein Size: 491 -
Molecular Weight
- 57 kDa
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Gene ID
- 27342
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NCBI Accession
- NM_014504, NP_055319
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UniProt
- A8K3R3
Target
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