RAD23 Homolog A (RAD23A) Peptide
RAD23A
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN982604
Quick Overview for RAD23 Homolog A (RAD23A) Peptide (ABIN982604)
Target
RAD23A
(RAD23 Homolog A (RAD23A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAD23A antibody (Catalog #: ARP42210_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAD23A (RAD23 Homolog A (RAD23A))
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Background
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RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: ATXN3,EP300,ATXN3,ATXN7,EP300,EWSR1,MPG,PDE6D,PSMD4,RPN1,SQSTM1,TRAF2,UBB,UBL7,UBQLN4,XPC,ATXN3,EWSR1,OTUD1,PDE6D,PSMD4,SQSTM1,TRAF2,UBI4,UBL7,XPC
Protein Size: 363 -
Molecular Weight
- 40 kDa
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Gene ID
- 5886
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NCBI Accession
- NM_005053, NP_005044
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UniProt
- P54725
Target
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