Retinoic Acid Receptor, beta (RARB) Peptide
RARB
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN982664
Quick Overview for Retinoic Acid Receptor, beta (RARB) Peptide (ABIN982664)
Target
Retinoic Acid Receptor beta (RARB)
(Retinoic Acid Receptor, beta (RARB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RARB antibody (Catalog #: ARP45601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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Background
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RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.
Alias Symbols: HAP, NR1B2, RRB2
Protein Interaction Partner: DNMT1,DNMT3A,DNMT3B,HDAC1,HIST4H4,MAP6,NCOA1,NCOA3,NCOR2,PNRC1,RXRA,RXRB,RXRG,SMAD2,CEBPA,CEBPB,NCOA1,NR4A2
Protein Size: 448 -
Molecular Weight
- 50 kDa
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Gene ID
- 5915
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NCBI Accession
- NM_000965, NP_000956
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UniProt
- P10826
Target
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