Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (Middle Region) Peptide
RDH12
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982814
$160.46
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100 μg
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Quick Overview for Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (Middle Region) Peptide (ABIN982814)
Target
RDH12
(Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RDH12 antibody (Catalog #: ARP52973_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
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Background
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RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Size: 316 -
Molecular Weight
- 35 kDa
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Gene ID
- 145226
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NCBI Accession
- NM_152443, NP_689656
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UniProt
- Q96NR8
Target
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