Nuclear Factor-kB p65 (NFkBP65) (Middle Region) Peptide
NFkBP65
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982835
Quick Overview for Nuclear Factor-kB p65 (NFkBP65) (Middle Region) Peptide (ABIN982835)
Target
NF-kB p65 (NFkBP65)
(Nuclear Factor-kB p65 (NFkBP65))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-REL antibody (Catalog #: ARP38198_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Nuclear Factor-kB p65 (NFkBP65) peptide
NFkBP65 Host: Synthetic Sodium azide
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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Background
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REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor. The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Alias Symbols: C-Rel
Protein Interaction Partner: CALM1,CCNE1,ELF1,GTF2B,HSPA8,MAP3K8,MAPK8,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,NOTCH1,PPP4C,REL,RELA,SP1,TBP,TNIP2,CDK2,ELF1,GTF2B,MAP3K8,MAPK8,MTPN,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,Nfkb1,PAPOLA,PPP4C,RELA,SP1,SRF,TBK1,TBP,TNIP2
Protein Size: 619 -
Molecular Weight
- 68 kDa
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Gene ID
- 5966
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NCBI Accession
- NM_002908, NP_002899
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UniProt
- Q04864
Target
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