Regulator of G-Protein Signaling 20 (RGS20) (N-Term) Peptide
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- Target See all RGS20 products
- RGS20 (Regulator of G-Protein Signaling 20 (RGS20))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NACCFCWCCC CSCSCLTVRN QEDQRPTIAS HELRADLPTW EESPAPTLEE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS20 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGS20 (Regulator of G-Protein Signaling 20 (RGS20))
- Background
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The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: GNAI1,GNAI3,GNAZ,OSTM1,STMN2,BOLA1,FAF2,GLRX3,GNAO1,GNAZ,MLF2,NSF,OSTM1,PMVK,RUVBL2,SET,SLC39A7,SPTLC1,STMN2,TRMT112,TXLNA,UBC
Protein Size: 241 - Molecular Weight
- 27 kDa
- Gene ID
- 8601
- NCBI Accession
- NM_003702, NP_003693
- UniProt
- O76081
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