Regulator of G-Protein Signaling 4 (RGS4) Peptide
RGS4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982937
Quick Overview for Regulator of G-Protein Signaling 4 (RGS4) Peptide (ABIN982937)
Target
RGS4
(Regulator of G-Protein Signaling 4 (RGS4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS4 antibody (Catalog #: ARP30213_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
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Background
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Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9
Protein Interaction Partner: CALM1,COPB1,COPB2,ERBB3,GNAI1,GNAI2,GNAO1,GNAQ,PLCB1,PTAFR,COPB2,ERBB3,GNAI1,GNAI1,GNAI2,GNAI2,GNAI3,GNAO1,GNAQ,GNAQ,GNAT1
Protein Size: 205 -
Molecular Weight
- 23 kDa
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Gene ID
- 5999
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NCBI Accession
- NM_005613, NP_005604
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UniProt
- P49798
Target
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