Regulator of G-Protein Signaling 4 (RGS4) Peptide
RGS4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RGS4 products
- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS4 antibody (Catalog #: ARP30213_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
- Background
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Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9
Protein Interaction Partner: CALM1,COPB1,COPB2,ERBB3,GNAI1,GNAI2,GNAO1,GNAQ,PLCB1,PTAFR,COPB2,ERBB3,GNAI1,GNAI1,GNAI2,GNAI2,GNAI3,GNAO1,GNAQ,GNAQ,GNAT1
Protein Size: 205 - Molecular Weight
- 23 kDa
- Gene ID
- 5999
- NCBI Accession
- NM_005613, NP_005604
- UniProt
- P49798
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