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Regulator of G-Protein Signaling 4 (RGS4) (C-Term) Peptide

RGS4 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN982938

Quick Overview for Regulator of G-Protein Signaling 4 (RGS4) (C-Term) Peptide (ABIN982938)

Target

RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequence

IFNLMEKDSY RRFLKSRFYL DLVNPSSCGA EKQKGAKSSA DCASLVPQCA

Characteristics

This is a synthetic peptide designed for use in combination with anti-RGS4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Regulator of G-Protein Signaling 4 (RGS4) peptide
RGS4 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Regulator of G-Protein Signaling 4 (RGS4) peptide
RGS4 Reactivity: Human Host: Synthetic BP, WB

Regulator of G-Protein Signaling 4 (RGS4) peptide
RGS4 Reactivity: Human, Cow, Mouse, Rabbit, Rat, Sheep Host: Synthetic BP

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Background

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

Alias Symbols: DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9

Protein Interaction Partner: CALM1,COPB1,COPB2,ERBB3,GNAI1,GNAI2,GNAO1,GNAQ,PLCB1,PTAFR,COPB2,ERBB3,GNAI1,GNAI1,GNAI2,GNAI2,GNAI3,GNAO1,GNAQ,GNAQ,GNAT1

Protein Size: 302

Molecular Weight

34 kDa

Gene ID

5999

NCBI Accession

NM_001102445, NP_001095915

UniProt

A7XA59

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