Ras Homolog Gene Family, Member B (RHOB) (Middle Region) Peptide
RHOB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RHOB products
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RHOB Antibody(ARP54702_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- Background
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RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alias Symbols: ARH6, ARHB, MST081, MSTP081, RHOH6
Protein Interaction Partner: ARHGDIG,ARHGEF3,FNTA,PDE6D,PGGT1B,PPP2CA,RHPN2,ARHGDIG,ARHGEF3,CIT,PDE6D,RHPN2
Protein Size: 196 - Molecular Weight
- 22 kDa
- Gene ID
- 388
- NCBI Accession
- NM_004040, NP_004031
- UniProt
- P62745
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