Ring Finger Protein 1 (RING1) (Middle Region) Peptide
RING1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982995
$160.46
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100 μg
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Quick Overview for Ring Finger Protein 1 (RING1) (Middle Region) Peptide (ABIN982995)
Target
RING1
(Ring Finger Protein 1 (RING1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RING1 antibody (Catalog #: ARP38202_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RING1 (Ring Finger Protein 1 (RING1))
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Background
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RING1 can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF1, RING1A
Protein Interaction Partner: BMI1,CBX4,RING1,FHL1,BMI1,CBX4,CBX7,CBX8,E2F6,ELAC2,FHL1,PHC1,RB1,RING1,RNF2,RYBP,BCOR,BMI1,Bmi1,CBX2,CBX3,CBX4,CBX7,CBX8,Cbx2,E2F1,E2F6,KDM5C,PCGF1,PCGF2,PHC1,RB1,RING1,RNF2,RYBP,cbx2
Protein Size: 406 -
Molecular Weight
- 42 kDa
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Gene ID
- 6015
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NCBI Accession
- NM_002931, NP_002922
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UniProt
- Q06587
Target
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