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Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40) Peptide

RNF40 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN983096
  • Target See all RNF40 products
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RNF40 antibody (Catalog #: ARP43165_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Background
    RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

    Alias Symbols: BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING

    Protein Interaction Partner: NCBP1,RB1,SPRYD5,UBE2L6,ZNF451,NCBP1,SPRYD5,STX1A,UBE2L6,USP15,ZNF451

    Protein Size: 1001
    Molecular Weight
    114 kDa
    Gene ID
    9810
    NCBI Accession
    NM_014771, NP_055586
    UniProt
    O75150
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