Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40) Peptide
RNF40
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN983096
Quick Overview for Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40) Peptide (ABIN983096)
Target
RNF40
(Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RNF40 antibody (Catalog #: ARP43165_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
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Background
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RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Alias Symbols: BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING
Protein Interaction Partner: NCBP1,RB1,SPRYD5,UBE2L6,ZNF451,NCBP1,SPRYD5,STX1A,UBE2L6,USP15,ZNF451
Protein Size: 1001 -
Molecular Weight
- 114 kDa
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Gene ID
- 9810
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NCBI Accession
- NM_014771, NP_055586
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UniProt
- O75150
Target
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