RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3) (Middle Region) Peptide
RNPC3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983111
Quick Overview for RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3) (Middle Region) Peptide (ABIN983111)
Target
RNP (RNPC3)
(RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RNPC3 antibody (Catalog #: ARP40868_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
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Background
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RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
Protein Interaction Partner: RNU11,RNU12-2P
Protein Size: 517 -
Molecular Weight
- 58 kDa
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Gene ID
- 55599
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NCBI Accession
- NM_017619, NP_060089
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UniProt
- Q96LT9
Target
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