Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2) (N-Term) Peptide
Quick Overview for Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2) (N-Term) Peptide (ABIN983113)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ROBO2 antibody (Catalog #: ARP45396_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))
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Background
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ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: KIAA1568, SAX3
Protein Interaction Partner: CPE,OLFM2,PPP1R1B,ROBO1,SLIT2,SLIT3,SSRP1,UBQLN4,CPE
Protein Size: 1378 -
Molecular Weight
- 151 kDa
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Gene ID
- 6092
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NCBI Accession
- NM_002942, NP_002933
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UniProt
- Q9HCK4
Target
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