Ribosomal Protein S6 (RPS6) (C-Term) Peptide
RPS6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983259
Quick Overview for Ribosomal Protein S6 (RPS6) (C-Term) Peptide (ABIN983259)
Target
RPS6
(Ribosomal Protein S6 (RPS6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- KKNKEEAAEY AKLLAKRMKE AKEKRQEQIA KRRRLSSLRA STSKSESSQK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RPS6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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Background
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: S6
Protein Interaction Partner: RPS6KB1,NDRG1,OLFM2,PAK2,RPS6KB1,RPS6KB2,STAU1,EIF3B,HSP90AA1
Protein Size: 249 -
Molecular Weight
- 27 kDa
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Gene ID
- 6194
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NCBI Accession
- NM_001010, NP_001001
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UniProt
- P62753
Target
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