Reticulon 4 (RTN4) Peptide
RTN4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983312
Quick Overview for Reticulon 4 (RTN4) Peptide (ABIN983312)
Target
Reticulon 4 (RTN4)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RTN4 antibody (Catalog #: ARP46813_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Reticulon 4 (RTN4)
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Background
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RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Alias Symbols: ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Protein Interaction Partner: RTN4IP1,UQCRC1,UQCRC2,BCL2,BCL2L1,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,LRCH4,LRPAP1,MBP,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SPG21,TUBA4A,UQCRC1,UQCRC2,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,KCNA1,KCNA2,LRCH4,LRPAP1,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SIRT2,SPG21,UQCRC1,UQCRC2,WWP1
Protein Size: 199 -
Molecular Weight
- 22 kDa
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Gene ID
- 57142
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NCBI Accession
- NM_007008, NP_008939
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UniProt
- Q7L7Q5
Target
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