Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide
RUNX1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN983319
Quick Overview for Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide (ABIN983319)
Target
RUNX1
(Runt-Related Transcription Factor 1 (RUNX1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RUNX1 antibody (Catalog #: ARP30954_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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Background
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal trans
Alias Symbols: AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Protein Interaction Partner: CBFB,TLE1,CBFB,TLE1,AR,CBFA2T2,CBFA2T3,CBFB,CCND1,CCND2,CCND3,CDK6,CEBPA,CEBPB,ELF2,ELF4,EP300,FOS,FOXP3,HIPK1,HIPK2,JUN,MYST3,MYST4,NCOR2,PAX5,SUV39H1,TLE1,TLE2,WWTR1,YAP1,AES,CBFA2T2,CBFB,CEBPB,EFNA2,ELF2,ELF4,ETS1,FHL2,FOS,JUN,LEF1,MYOD1,MYST4,PAX5,SMAD1,SMAD2,SMAD3,SMAD5,SUV39H1,TLE1,TRAF6,VDR,YAP1
Protein Size: 453 -
Molecular Weight
- 49 kDa
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Gene ID
- 861
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NCBI Accession
- NM_001001890, NP_001001890
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UniProt
- Q01196
Target
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