Syndecan Binding Protein (Syntenin) (SDCBP) Peptide
SDCBP
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN983477
Quick Overview for Syndecan Binding Protein (Syntenin) (SDCBP) Peptide (ABIN983477)
Target
SDCBP
(Syndecan Binding Protein (Syntenin) (SDCBP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SDCBP antibody (Catalog #: ARP44535_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
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Background
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SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: MDA-9, ST1, SYCL, TACIP18
Protein Interaction Partner: EFNB2,EPHA7,NF2,NRXN1,SDC3,TGFA,CADM1,CD6,EFNB1,EFNB2,EPHB2,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRM3,IL5RA,NF2,NFASC,PTPRJ,RAB5A,RNF11,SDC1,SDC2,SDC4,SDCBP,SDCBP2,SLC6A5,SOX4,STX1A,TGFA,ULK1,WDR91,EFNB1,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRIK3,GRM3,GRM7,IL5RA,NF2,PTPRJ,RAB5A,SDC1,SDC2,SOX4,TRAF6,ULK1
Protein Size: 298 -
Molecular Weight
- 32 kDa
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Gene ID
- 6386
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NCBI Accession
- NM_001007067, NP_001007068
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UniProt
- O00560
Target
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