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SECIS Binding Protein 2 (SECISBP2) (N-Term) Peptide

SECISBP2 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN983509

Quick Overview for SECIS Binding Protein 2 (SECISBP2) (N-Term) Peptide (ABIN983509)

Target

SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequence

FDSERADGTI SSEIKSARGS HHLSIYAENS LKSDGYHKRT DRKSRIIAKN

Characteristics

This is a synthetic peptide designed for use in combination with anti-SECISBP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
SECIS Binding Protein 2 (SECISBP2) peptide
SECISBP2 Host: Synthetic BP, Imm

SECIS Binding Protein 2 (SECISBP2) peptide
SECISBP2 Reactivity: Human Host: Synthetic BP, BI

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Background

The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Alias Symbols: DKFZp686C09169, SBP2

Protein Interaction Partner: ATXN7L3,SMAD9

Protein Size: 854

Molecular Weight

95 kDa

Gene ID

79048

NCBI Accession

NM_024077, NP_076982

UniProt

Q96T21

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