Pre-mRNA Branch Site Protein p14 (SF3B14) Peptide
SF3B14
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983624
Quick Overview for Pre-mRNA Branch Site Protein p14 (SF3B14) Peptide (ABIN983624)
Target
Pre-mRNA Branch Site Protein p14 (SF3B14)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SF3B14 antibody (Catalog #: ARP40829_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Pre-mRNA Branch Site Protein p14 (SF3B14)
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Background
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SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Protein Interaction Partner: SF3B1,SF3B1,SF3B14,SF3A2,SF3B1
Protein Size: 125 -
Molecular Weight
- 14 kDa
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Gene ID
- 51639
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NCBI Accession
- NM_016047, NP_057131
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UniProt
- Q7RTV0
Target
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