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serine/arginine-Rich Splicing Factor 2 (SRSF2) (C-Term) Peptide

SRSF2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983647

Quick Overview for serine/arginine-Rich Splicing Factor 2 (SRSF2) (C-Term) Peptide (ABIN983647)

Target

SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    KSKSSSVSRS RSRSRSRSRS RSPPPVSKRE SKSRSRSKSP PKSPEEEGAV

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-SFRS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

    Background

    The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.

    Alias Symbols: PR264, SC-35, SC35, SFRS2A, SRp30b, SFRS2

    Protein Size: 221

    Molecular Weight

    25 kDa

    Gene ID

    6427

    NCBI Accession

    NM_003016, NP_003007

    UniProt

    Q01130
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