serine/arginine-Rich Splicing Factor 2 (SRSF2) (C-Term) Peptide
SRSF2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SRSF2 products
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KSKSSSVSRS RSRSRSRSRS RSPPPVSKRE SKSRSRSKSP PKSPEEEGAV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SFRS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
- Background
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The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.
Alias Symbols: PR264, SC-35, SC35, SFRS2A, SRp30b, SFRS2
Protein Size: 221 - Molecular Weight
- 25 kDa
- Gene ID
- 6427
- NCBI Accession
- NM_003016, NP_003007
- UniProt
- Q01130
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