Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (Middle Region) Peptide
SGCB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983668
$160.46
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100 μg
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Quick Overview for Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (Middle Region) Peptide (ABIN983668)
Target
SGCB
(Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SGCB antibody (Catalog #: ARP44244_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
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Background
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SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD, MIM 300377) and syntrophin (SNTA1, MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA, MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442
Alias Symbols: A3b, LGMD2E, SGC
Protein Interaction Partner: SGCA,SGCD,SGCG,SGCZ
Protein Size: 318 -
Molecular Weight
- 35 kDa
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Gene ID
- 6443
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NCBI Accession
- NM_000232, NP_000223
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UniProt
- Q16585
Target
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