Nucleotide Exchange Factor SIL1 (SIL1) (C-Term) Peptide
Quick Overview for Nucleotide Exchange Factor SIL1 (SIL1) (C-Term) Peptide (ABIN983748)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIL1 antibody (Catalog #: ARP44850_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))
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Background
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SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Alias Symbols: BAP, MSS, ULG5
Protein Interaction Partner: HSPA5,SMAD9,HSPA5
Protein Size: 461 -
Molecular Weight
- 49 kDa
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Gene ID
- 64374
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NCBI Accession
- NM_001037633, NP_001032722
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UniProt
- Q9H173
Target
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