Stem-Loop Binding Protein (SLBP) Peptide
Quick Overview for Stem-Loop Binding Protein (SLBP) Peptide (ABIN983804)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SLBP antibody (Catalog #: ARP40657_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SLBP (Stem-Loop Binding Protein (SLBP))
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Background
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SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
Alias Symbols: HBP
Protein Interaction Partner: LSM10,USP8,ZNF473,ERI1,ZNF473
Protein Size: 270 -
Molecular Weight
- 30 kDa
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Gene ID
- 7884
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NCBI Accession
- NM_006527, NP_006518
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UniProt
- Q14493
Target
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