Helicase-Like Transcription Factor (HLTF) Peptide
HLTF
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984111
Quick Overview for Helicase-Like Transcription Factor (HLTF) Peptide (ABIN984111)
Target
HLTF
(Helicase-Like Transcription Factor (HLTF))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMARCA3 antibody (Catalog #: ARP38218_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HLTF (Helicase-Like Transcription Factor (HLTF))
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Background
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SMARCA3 (HLTF) is a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA3 contains a RING finger DNA binding motif. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform which is truncated at the N-terminus as compared to the full-length protein.
Alias Symbols: ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3
Protein Interaction Partner: EEF1G,PCNA,RAD18,RPAP1,UBE2N,UBE2V2,USP7
Protein Size: 1009 -
Molecular Weight
- 114 kDa
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Gene ID
- 6596
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NCBI Accession
- NM_139048, NP_620636
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UniProt
- Q14527
Target
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