Survival Motor Neuron Domain Containing 1 (SMNDC1) (Middle Region) Peptide
SMNDC1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN984137
Quick Overview for Survival Motor Neuron Domain Containing 1 (SMNDC1) (Middle Region) Peptide (ABIN984137)
Target
SMNDC1
(Survival Motor Neuron Domain Containing 1 (SMNDC1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMNDC1 antibody (Catalog #: ARP40612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))
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Background
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This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Alias Symbols: SMNR, SPF30
Protein Interaction Partner: KPNB1,SNRNP200,SNRPB,CDK5RAP3,DDX21,EWSR1,FDFT1,PPAN,RNMTL1,RPL3,RUVBL1,SF3A2,SF3A3,SF3B1,SF3B2,SF3B3,SF3B4,SNRNP200,TSR1,mad2
Protein Size: 238 -
Molecular Weight
- 27 kDa
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Gene ID
- 10285
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NCBI Accession
- NM_005871, NP_005862
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UniProt
- O75940
Target
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