Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (Middle Region) Peptide
SMPD1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984138
Quick Overview for Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (Middle Region) Peptide (ABIN984138)
Target
SMPD1
(Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMPD1 antibody (Catalog #: ARP35630_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
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Background
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SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB).
Alias Symbols: ASM, NPD, ASMASE
Protein Interaction Partner: ASAH1,NGFRAP1
Protein Size: 631 -
Molecular Weight
- 65 kDa
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Gene ID
- 6609
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NCBI Accession
- NM_000543, NP_000534
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UniProt
- P17405
Target
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