Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide
SNRPB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984197
Quick Overview for Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide (ABIN984197)
Target
SNRPB
(Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SNRPB antibody (Catalog #: ARP40443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))
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Background
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SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
Alias Symbols: COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'
Protein Interaction Partner: GEMIN6,RBBP6,SMN1,ASCC2,C14orf1,CD2BP2,CLNS1A,COIL,CTDP1,DDX20,DHX9,GEMIN4,GEMIN5,GEMIN6,GEMIN7,GIGYF2,LSM11,PRMT5,PSMA3,SKIV2L,SMN2,SMN2,SMNDC1,SNRPB,SNRPD1,SNRPD3,STRAP,STXBP2,STXBP3,TOP3B,WBP4,WDR77,AIRE,ASCC2,C14orf1,CLNS1A,COIL,DDX20,DYNC1H1,EFTUD2,FNBP4,GEMIN4,GEMIN6,GEMIN7,HTATSF1,KHK,LGALS1,MEPCE,PRPF8,PSMA3,SART3,SF3A2,SMN1,SMN2,SNRNP200,SNRPD3,SNUPN,TOP3B,WBP4,WDR77
Protein Size: 231 -
Molecular Weight
- 24 kDa
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Gene ID
- 6628
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NCBI Accession
- NM_003091, NP_003082
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UniProt
- Q66K91
Target
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