Snurportin 1 (SNUPN) (Middle Region) Peptide
SNUPN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984212
Quick Overview for Snurportin 1 (SNUPN) (Middle Region) Peptide (ABIN984212)
Target
Snurportin 1 (SNUPN)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SNUPN antibody (Catalog #: ARP40598_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Snurportin 1 (SNUPN)
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Background
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: KPNBL, RNUT1, Snurportin1
Protein Interaction Partner: ENO2,KPNB1,PAFAH1B2,PEX5,RPL17,TNNT3,XPO1,DDX20,ENO2,KPNB1,PEX5,RAN,SMN1,SNRPB,TNNT3,XPO1,ZNF259
Protein Size: 360 -
Molecular Weight
- 41 kDa
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Gene ID
- 10073
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NCBI Accession
- NM_005701, NP_005692
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UniProt
- O95149
Target
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