Sorting Nexin 1 (SNX1) (N-Term) Peptide
SNX1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984213
Quick Overview for Sorting Nexin 1 (SNX1) (N-Term) Peptide (ABIN984213)
Target
Sorting Nexin 1 (SNX1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- EDIFTGAAVV SKHQSPKITT SLLPINNGSK ENGIHEEQDQ EPQDLFADAT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SNX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Sorting Nexin 1 (SNX1)
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Background
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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: HsT17379, MGC8664, SNX1A, Vps5, VPS5
Protein Interaction Partner: ACVR1B,ACVR2B,EGFR,F2R,HGS,INSR,LEPR,PDGFRB,SNX1,SNX2,SNX6,VPS35,ACVR1B,ACVR2B,ATXN7,EGFR,F2R,HGS,INSR,LEPR,PDGFRB,SNX1,SNX2,SNX6,TK1,UFD1L
Protein Size: 557 -
Molecular Weight
- 63 kDa
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Gene ID
- 6642
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NCBI Accession
- NM_001242933, NP_001229862
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UniProt
- Q13596
Target
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