Sterol O-Acyltransferase 1 (SOAT1) (Middle Region) Peptide
Quick Overview for Sterol O-Acyltransferase 1 (SOAT1) (Middle Region) Peptide (ABIN984225)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- ASRFIIIFEQ IRFVMKAHSF VRENVPRVLN SAKEKSSTVP IPTVNQYLYF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SOAT1 Antibody(ARP45419_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))
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Background
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Acyl-coenzyme A:cholesterol acyltransferase (ACACT, EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]).
Alias Symbols: ACACT, ACAT, ACAT1, RP11-215I23.2, SOAT, STAT
Protein Size: 550 -
Molecular Weight
- 65 kDa
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Gene ID
- 6646
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NCBI Accession
- NM_003101, NP_003092
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UniProt
- P35610
Target
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