Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptide
Src
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984405
$160.46
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100 μg
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Quick Overview for Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptide (ABIN984405)
Target
Src
(Proto-oncogene tyrosine-protein kinase Src (Src))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SRC antibody (Catalog #: ARP32476_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Target Type
- Viral Protein
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Background
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer.This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: E2F4,ABL1,BCAR1,BCR,CDCP1,DRD4,ERBB2,ETS1,ETS2,GJA1,GJB1,HNRNPK,KHDRBS1,MUC1,PDE4D,PDGFRB,PTK2,PTK2,PTPN2,RGS16,SHB,SHC1,SRC,ABL1,ACTN1,ADAM12,ADAM15,ADRB2,ADRB3,ADRBK1,AFAP1,AFAP1L2,AKT1,ANKRD11,ANXA1,ANXA2,AR,ARHGAP1,ARHGAP32,ARR3,ASAP1,ATP2B4,AXL,BCAR1,BCR,BMX,CAV1,CAV2,CBL,CBLC,CD2AP,CD33,CD36,CD46,CD59,CDCP1,CDH5,CDK5,CDKN1B,CEACAM1,CEACAM3,CHUK,CNTNAP1,CSK,CTNNB1,CTNND1,CTTN,DAB1,DAB2,DAG1,DAPP1,DDR2,DGKA,DGKZ,DLG4,DNM1,DNM2,DOK1,DOK2,DOK4,EFNB1,EFNB2,EGFR,EPHB2,EPS8,ERBB2,ESR1,ESR2,ETS1,ETS2,EVL,FARP2,FASLG,FGR,FHIT,FOXO1,FRS2,FYB,GAB2,GAB3,GFAP,GIT1,GJA1,GJB1,GNB2L1,GRB10,GRB2,GRIN2A,GRIN2B,GRLF1,GTF2I,GUCY2C,HLA-A,HLA-B,HNF1A,HNRNPK,HRAS,HSP90AA1,IGF1R,IKBKB,IKBKG,IL6R,INPPL1,INSR,ITGB3,JUP,KCNA5,KCNB1,KCNQ5,KDR,KHDRBS1,KIFAP3,KIT,LRP1,MAPK15,MATK,MED28,MET,MPZL1,MST1R,MUC1,MYLK,ND2,NFKBIA,NMT1,NOS2,NPHS1,NR1I2,P2RY2,PAK2,PDCD6IP,PDE6G,PDGFRB,PDPK1,PECAM1,PGR,PIK3R1,PKD1,PLCG1,PPARD,PPP2R4,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCI,PRKCZ,PRKD1,PTK2,PTK2B,PTPN1,PTPN11,PTPN18,PTPN2,PTPN21,PTPN6,PTPRA,PTPRE,PXN,RAF1,RASA1,RET,RGS16,RXRA,SH2D3C,SH3BP1,SH3PXD2A,SHB,SHC1,SKAP1,SLC9A2,SMARCB1,SMARCE1,SPTAN1,SRC,SRF,STAP2,STAT1,STAT3,STAT5A,STAT5B,STAT6,SYK,SYN1,TERT,THRA,TIAM1,TNFRSF11A,TRAF1,TRAF3,TRAF6,TRAT1,TRIP10,TRIP6,TRPC6,TRPV4,TUB,TXK,TYRO3,VCL,VIL1,WAS,WBP11,WWOX,YTHDC1,YWHAB,YWHAE,YWHAG,YWHAH,ABL1,ADRB2,ADRB3,ADRBK1,AHR,AR,ARHGAP1,ARHGAP17,ARHGAP32,ARHGAP32,ARNT,ARR3,ASAP1,ASAP2,AXL,Adrb3,BCAR1,BMX,CAV1,CAV2,CBL,CD44,CD46,CDC25C,CDC37,CDH1,CRK,CSF1R,CSK,CTNND1,DAB2,DAG1,DDR2,DOCK1,DOK1,DOK4,EFNB1,EGFR,EP300,EPHA3,EPHA4,EPHB2,EPS8,ERBB2,ESR1,ESR2,EVL,FOXO1,FYN,GAB2,GAB3,GNB2L1,GRB10,GRB2,GRIN2A,GSN,HNF1A,HSP90AA1,ITK,KHDRBS1,KIFAP3,LRP1,LYN,MAP2,MAPK8IP3,MATK,MET,MICAL1,MPZL1,MUC1,MYLK,NCOA6,ND2,PDE6G,PECAM1,PELP1,PIK3R1,PLCG1,PLD1,PLD2,PLSCR1,PRKCZ,PTK2,PTK2B,PTPN21,PTPRA,PXN,RAF1,RARA,RASA1,RET,RPL10,RPS6KB1,RPS6KB2,RXRA,SH3BP1,SHB,SKAP1,SLC9A2,SNURF,SRF,STAT1,STAT3,SYK,SYN1,THRB,TNFSF11,TRAF1,TRAF3,TRAF6,TRIP4,TRIP6,TRPC6,TRPV4,TYRO3,WAS
Protein Size: 536 -
Molecular Weight
- 60 kDa
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Gene ID
- 6714
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NCBI Accession
- NM_005417, NP_005408
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UniProt
- P12931
Target
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