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Sjogren Syndrome Antigen B (SSB) Peptide

SSB Reactivity: Human, Mouse Host: Synthetic BP, WB, IHC
Catalog No. ABIN984447
  • Target See all SSB products
    SSB (Sjogren Syndrome Antigen B (SSB))
    Origin
    Human, Mouse
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SSB antibody (Catalog #: ARP40462_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SSB (Sjogren Syndrome Antigen B (SSB))
    Background
    SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006).[supplied by OMIM].

    Alias Symbols: La, LARP3

    Protein Interaction Partner: HCVgp1,SNORD3A,NCL,SSB,NCL,PMVK,PUF60

    Protein Size: 408
    Molecular Weight
    45 kDa
    Gene ID
    6741
    NCBI Accession
    NM_003142, NP_003133
    UniProt
    P05455
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