Stanniocalcin 2 (STC2) (C-Term) Peptide
STC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984547
Quick Overview for Stanniocalcin 2 (STC2) (C-Term) Peptide (ABIN984547)
Target
Stanniocalcin 2 (STC2)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- HHLPEPSSRE TGRGAKGERG SKSHPNAHAR GRVGGLGAQG PSGSSEWEDE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-STC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Stanniocalcin 2 (STC2)
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Background
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This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Alias Symbols: STC-2, STCRP
Protein Size: 302 -
Molecular Weight
- 31 kDa
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Gene ID
- 8614
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NCBI Accession
- NM_003714, NP_003705
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UniProt
- O76061
Target
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