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Sulfatase 2 (SULF2) Peptide

SULF2 Reactivity: Human Host: Synthetic BP, IHC, WB

Catalog No. ABIN984614

Quick Overview for Sulfatase 2 (SULF2) Peptide (ABIN984614)

Target

SULF2 (Sulfatase 2 (SULF2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)

Characteristics

This is a synthetic peptide designed for use in combination with anti-SULF2 antibody (Catalog #: ARP49338_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Sulfatase 2 (SULF2) peptide
SULF2 Reactivity: Mammalian Host: Synthetic BP, IHC, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

SULF2 (Sulfatase 2 (SULF2))

Background

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].

Alias Symbols: DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411

Protein Size: 870

Molecular Weight

98 kDa

Gene ID

55959

NCBI Accession

NM_018837, NP_061325

UniProt

Q8IWU5

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