Surfeit 1 (SURF1) (N-Term) Peptide
SURF1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984639
Quick Overview for Surfeit 1 (SURF1) (N-Term) Peptide (ABIN984639)
Target
SURF1
(Surfeit 1 (SURF1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GLRAAGLGRA PASAAWRSVL RVSPRPGVAW RPSRCGSSAA EASATKAEDD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SURF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SURF1 (Surfeit 1 (SURF1))
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Background
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This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Alias Symbols: -
Protein Size: 300 -
Molecular Weight
- 33 kDa
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Gene ID
- 6834
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NCBI Accession
- NM_003172, NP_003163
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UniProt
- Q15526
Target
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