Spleen tyrosine Kinase (SYK) (Middle Region) Peptide
SYK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984661
Quick Overview for Spleen tyrosine Kinase (SYK) (Middle Region) Peptide (ABIN984661)
Target
SYK
(Spleen tyrosine Kinase (SYK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RIKSYSFPKP GHRKSSPAQG NRQESTVSFN PYEPELAPWA ADKGPQREAL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SYK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Background
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This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp313N1010, FLJ25043, FLJ37489, p72-Syk
Protein Interaction Partner: CRKL,EZR,HHV4gp002,MSN,STAT1,STAT1,SYK,UBB,BLNK,BTK,CBL,CBLB,CD19,CD22,CD3E,CD79A,CD79B,CRKL,CSF2RB,CSF3R,CTTN,DBNL,DUSP3,EPOR,FCER1G,FCGR1A,FCGR2A,FGR,FYN,GAB2,GRB2,HCLS1,HNRNPU,IL2RB,ITGB2,JAK1,LAT,LAX1,LCK,LCP2,LYN,MAP4K1,MAPK3,MS4A2,NFAM1,PAG1,PIK3AP1,PIK3R1,PIK3R2,PLCG1,PLCG2,POU2AF1,PRKCA,PRKD1,PTK2,PTK2B,PTPN6,PXN,RASA1,RPS6KA1,SELPLG,SH2B2,SH3BP2,SHC1,SIT1,SLA,SLC4A1,SNCA,SRC,STAT1,STAT3,STAT5A,SYK,TLR4,TNFRSF1A,TRAF6,TUBA1A,TUBA4A,TYROBP,UBB,VAV1,VAV2,CALM1,CBL,CBLB,CD19,CD22,CD3E,CD4,CD72,CD79A,CD79B,CRKL,CSF3R,CTTN,Cbl,EPOR,FCER1G,FCGR2A,FCRL3,FGR,FYN,GRB2,HDAC1,HDAC2,HDAC3,HDAC4,HDAC6,HDAC9,ITGB2,LAT,LCK,LYN,MS4A2,PAG1,PLCG1,PLCG2,PRKD1,PTK2,PTK2B,PTPN6,PXN,RPS6KB1,RPS6KB2,SH3BP2,SIRPB1,SIT1,SLA,SP1,SRC,SYK,TRAF6,TUBA1A,TUBG1,UBC,Ubc,VAV1
Protein Size: 635 -
Molecular Weight
- 72 kDa
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Gene ID
- 6850
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NCBI Accession
- NM_003177, NP_003168
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UniProt
- P43405
Target
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